# Five research peptides compared Canonical: https://europeanpeptideshop.com/blog/kpv-mots-c-tb-500-semax-epitalon-explained/ Explore the catalogue and research library. Ordering and shipping have not opened yet. Compound research · 8 November 2026 · 2 min read · By [European Peptide Shop](https://europeanpeptideshop.com/about/) ### On this page A US draft policy from the Department of Health and Human Services (HHS) names six peptides. This page sets out what each is as a molecule and what the policy documents say about the evidence. It does not alter UK rules, which are covered in [is BPC-157 legal in the UK](https://europeanpeptideshop.com/blog/is-bpc-157-legal-in-the-uk/). ## What is each of the six peptides? Peptide | What it is [BPC-157](https://europeanpeptideshop.com/blog/bpc-157-research/) | Synthetic 15-amino-acid peptide derived from a gastric protein sequence [TB-500](https://europeanpeptideshop.com/blog/tb-500-thymosin-beta-4/) | Synthetic 7-amino-acid fragment of thymosin beta-4 (Ac-LKKTETQ) [MOTS-c](https://europeanpeptideshop.com/blog/mots-c/) | 16-amino-acid peptide encoded in mitochondrial DNA [KPV](https://europeanpeptideshop.com/blog/kpv-research/) | Lys-Pro-Val, a three-amino-acid fragment of alpha-melanocyte-stimulating hormone [Semax](https://europeanpeptideshop.com/blog/semax-research/) | Synthetic heptapeptide analogue of an ACTH fragment, with a Pro-Gly-Pro tail Epitalon | Synthetic tetrapeptide (Ala-Glu-Asp-Gly) TB-500 is a short fragment, not thymosin beta-4 itself, which is a 43-amino-acid protein. ## What did HHS say about the evidence? HHS described FDA scientists' concerns about TB-500, Epitalon and Semax as "inferential or mechanistic rather than observed", and for KPV as reflecting "an absence of information". FDA briefing materials called the BPC-157 studies limited in size and duration, without establishing safety or effectiveness. ## EPS documentation Use the [research catalogue](https://europeanpeptideshop.com/shop/) to check the exact name, labelled amount and format. The [COA library](https://europeanpeptideshop.com/coa/) publishes the original Janoshik reports selected for EPS, retaining the original report client name and any missing batch fields. Literature findings and another supplier's analytical results are not evidence about an EPS batch. ## Laboratory research only Materials listed on this site are supplied for in-vitro laboratory research and are not for use in or on humans or animals. They are not medicines. This article summarises published work and gives no dosing, administration, treatment or in-vivo guidance. Findings from a study apply to the material and conditions of that study, and they say nothing about any product listed here. ## References - [AJMC, 29 October 2026](https://www.ajmc.com/view/hhs-draft-policy-eases-enforcement-on-6-compounded-peptides) ## Related listings [10 mg](https://europeanpeptideshop.com/shop/tb-500-10mg/) Tissue repair research ### [TB-500](https://europeanpeptideshop.com/shop/tb-500-10mg/) 10 mg · Lyophilised powder Ordering opens later. Prices and availability are not yet published.[Details](https://europeanpeptideshop.com/shop/tb-500-10mg/) [10 mg](https://europeanpeptideshop.com/shop/mots-c-10mg/) Mitochondrial research ### [MOTS-C](https://europeanpeptideshop.com/shop/mots-c-10mg/) 10 mg · Lyophilised powder Ordering opens later. Prices and availability are not yet published.[Details](https://europeanpeptideshop.com/shop/mots-c-10mg/) [10 mg](https://europeanpeptideshop.com/shop/semax-10mg/) Nootropic research ### [Semax](https://europeanpeptideshop.com/shop/semax-10mg/) 10 mg · Lyophilised powder Ordering opens later. Prices and availability are not yet published.[Details](https://europeanpeptideshop.com/shop/semax-10mg/) ## More articles Compound research · 3 min read ## [How MOTS-c affects cell signalling](https://europeanpeptideshop.com/blog/mots-c-how-it-works/) MOTS-c is studied for its role in how cells handle changes in energy. This plain-English guide explains the main experiments and their limits. 8 November 2026 Compound research · 6 min read ## [Semax research and evidence](https://europeanpeptideshop.com/blog/semax-research/) An evidence-tiered review of the Semax literature: in-vitro, animal and human findings, and what cannot be concluded from them. 8 November 2026 Compound research · 4 min read ## [TB-500 versus thymosin beta-4](https://europeanpeptideshop.com/blog/tb-500-thymosin-beta-4/) Understand TB-500 and thymosin beta-4 naming, full-length versus fragment identities, and the batch-report checks needed for a 10mg listing. 8 November 2026